Modified insulin-like growth factor studied in receptor signaling research.
IGF-1 LR3 is a long-acting variant of insulin-like growth factor-1, modified by amino-acid substitution and chain extension.
The modifications reduce binding to IGF binding proteins and extend receptor interaction time in experimental models.
Referenced in cell growth, receptor signaling, and molecular biology research involving the IGF axis.
IGF receptor signaling, cell proliferation models, molecular growth studies.